Resultados de eficácia deca durabolin

Como coadjuvante para terapias específicas e medidas dietéticas em várias condições patológicas caracterizadas por um balanço negativo de nitrogênio1
No que diz respeito ao catabolismo de proteínas, o tratamento de DECA-DURABOLIN® induz um aumento favorável na massa magra do corpo, no peso corpóreo e outros parâmetros da composição do corpo em homens e mulheres que apresentam uma diminuição do peso corpóreo que não pode ser revertido somente por medidas dietéticas. O aumento na massa magra do corpo é frequentemente acompanhado por melhorias da energia e da fadiga, função física e qualidade de vida. Estes efeitos de DECA- DURABOLIN® são observados independentemente das circunstâncias subjacentes que causam o balanço negativo do nitrogênio (por exemplo a depleção por HIV, doença pulmonar obstrutiva crônica, tratamento citostático ou por glicocorticoide e infecção crônica).

Tratamento da osteoporose 2
Os estudos clínicos demonstram que o tratamento com DECA-DURABOLIN® causa a inibição significante da reabsorção e um aumento na formação do osso, resultando em um aumento da quantidade de mineral no osso e, consequentemente, uma redução na taxa de fraturas de acordo com alguns estudos. Na maioria dos estudos clínicos, as avaliações da massa óssea demonstraram uma diferença significativa em favor de DECA-DURABOLIN® em mulheres e homens independentemente da causa da osteoporose, como a menopausa, o envelhecimento ou o tratamento com glicocorticoide. Igualmente na osteoporose estabelecida, DECA- DURABOLIN® aumentou a densidade mineral óssea sem efeitos secundários significativos. A diferença persistiu durante o ano após o término do tratamento.

Tratamento da anemia da insuficiência renal crônica, anemia aplástica e anemia devido a tratamentos citotóxicos3
O tratamento da anemia depois de uma diálise devido à insuficiência renal crônica com a monoterapia de DECA-DURABOLIN®(100-200 mg/semana) resultou, particularmente em homens idosos, em um aumento favorável nos parâmetros hematológicos. A combinação de baixa dose de DECA-DURABOLIN® (50-100 mg/semana) com eritropoietina recombinante humana (rhEPO), especialmente em jovens do sexo masculino e feminino, pode permitir uma redução da dose de eritropoietina. DECA- DURABOLIN® (50-200 mg/semana) pode ser recomendado como um coadjuvante na anemia aplástica, anemia devido a tratamentos citotóxicos ou doença de Fanconi. Na anemia aplástica grave, DECA-DURABOLIN® pode aumentar o número de respondedores ao tratamento imunossupressor. Baseado nos efeitos positivos de DECA-DURABOLIN® na hematopoiese, considera-se provavelmente que DECA-DURABOLIN® (50-200 mg/1-2 semanas) pode contribuir com a restauração da anemia devido a tratamentos citotóxicos, como é suportado por algumas observações clínicas.

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