Eficácia de aminoácidos em nutrição parenteral foi demonstrada nos seguintes estudos: “Amino acid requirements of man”.
(ROSE W. C.; 1949), “Amino acid and energy metabolism in septic and traumatized patients.” (CLOWES G, RANDALL H.T.; 1980), “Parenteral nutrition. An update on amino acid formulation.” (GEISSER P, SUTTER H.P., HOHL H.; 1988), “Amino acid metabolism during total parenteral nutrition in healthy volunteers: evaluation of a new amino acid solution.”( BERARD M.P, HANKARD R, CYNOBER L; 2001); “Evaluation of clinical safety and efficiency of a new amino acid solution with electrolytes (AFD 10% E)” (ZUMTOBEL V et al.; 2001).