A eficácia de glibenclamida está comprovada nos seguintes estudos: “Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34).” (Anon, 1998b); ”Daytime glibenclamide and bedtime NPH insulin compared to intensive insulin treatment in secondary sulphonylurea failure: a 1-year follow- up.” (Clauson, P. 1996); “Efficacy of glyburide in diabetics poorly controlled on first- generation oral hypoglycemics.” (Cohen, K.L. 1987); “New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus” (DeFronzo, R.A. 1983); “Oral hypoglycemic drugs for gestational diabetes.” (Greene, M.F. 2000); ”Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations: a double-blind controlled study.” (Hermann, L.S. 1994); “Comparison of glibenclamide, gliquidone, glisoxepide, and placebo in maturity onset diabetics of differing degrees of severity.” (Irsigler, K. 1979); “Efficacy of insulin and sulfonylurea combination therapy in type II diabetes: a meta-analysis of the randomized placebo-controlled trials.” (Johnson, J.L. 1996) “Effects of a combination of bedtime intermediate-acting insulin and glibenclamide in type 2 (non-insulin-dependent) diabetic patients with secondary failure to respond to oral hypoglycaemic agents.” (Krempf, M. 1992); “A comparison of glyburide and insulin in women with gestational diabetes mellitus.” (Langer, O. 2000); ”Glyburide and glipizide in treatment of diabetic patients with secondary failures to tolazamide or chlorpropamide.” (Lev, J.D. 1987) ; “Maximal dose glyburide therapy in markedly symptomatic patients with type 2 diabetes: a new use for an old friend.” (Peters, A.L. 1996); ”The effect of combination treatment with acarbose and glibenclamide on postprandial glucose and insulin profiles: additive blood glucose lowering effect and decreased hypoglycaemia.” (Rosak, C. 2002); ”Over-all therapeutic usefulness of glybenclamide, a new hypoglycemic sulfonylurea.” (Rull, J.A. 1970); ”Addition of sulfonylurea to insulin treatment in poorly controlled type II diabetes :a double-blind, randomized clinical trial.” (Schade, D.S. 1987); “Treatment of adult diabetes with semi-euglucon. Munch Med Wochenschr.” (Schafer, D. 1979); “Comparison of different insulin regimens in elderly patients with NIDDM.” (Wolffenbuttel, B.H.R. 1996); “Comparison of bedtime insulin regimens in patients with type 2 diabetes mellitus: a randomized, controlled trial.” (Yki- Jarvinen, H. 1999).
Resultados de eficácia daonil
DAONIL com posologia, indicações, efeitos colaterais, interações e outras informações. Todas as informações contidas na bula de DAONIL têm a intenção de informar e educar, não pretendendo, de forma alguma, substituir as orientações de um profissional médico ou servir como recomendação para qualquer tipo de tratamento. Decisões relacionadas a tratamento de pacientes com DAONIL devem ser tomadas por profissionais autorizados, considerando as características de cada paciente.